tag:blogger.com,1999:blog-35997458635844014.post5107886884548502677..comments2023-04-09T09:54:31.911-04:00Comments on Cancer Stem Cell News: A review of the CSC paradigmJim Tillhttp://www.blogger.com/profile/02092503335133096747noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-35997458635844014.post-272564881998095042009-07-06T11:22:17.801-04:002009-07-06T11:22:17.801-04:00See also: Rumsfeldian Stem Cells by Nicholas Wade,...See also: <a href="http://tierneylab.blogs.nytimes.com/2009/07/02/rumsfeldian-stem-cells/" rel="nofollow">Rumsfeldian Stem Cells</a> by Nicholas Wade, <em>TierneyLab Blog</em>, The New York Times, July 2, 2009. Excerpt: "<em>The most interesting topic in Science’s special issue is that of cancer stem cells, the idea that cancers are caused by a few errant stem cells that generate the mass of a tumor, and that chemotherapy may be ineffective because it kills most tumor cells <a href="http://www.sciencemag.org/cgi/content/abstract/324/5935/1670" rel="nofollow">but fails to target the cancer stem cells</a></em>."Jim Tillhttps://www.blogger.com/profile/02092503335133096747noreply@blogger.comtag:blogger.com,1999:blog-35997458635844014.post-10713450059223441712009-06-26T21:42:39.776-04:002009-06-26T21:42:39.776-04:00The fact that cancer stem cells (CSCs) may have un...The fact that cancer stem cells (CSCs) may have unique biological properties more likely to fuel cancer, or unfavorable factors in the neighboring cells surrounding the tumor, such as mutated genes, proteins that encourage cell growth, it is important to look at the "forest" and not just the "trees." There are many pathways to altered cellular (forest) function (hence all the different "trees" which correlate in different situations). Cell functional analysis measures what happens at the end (the effects on the forest), rather than the status of the individual trees.Greg Pawelskihttps://www.blogger.com/profile/13881517358316630729noreply@blogger.com