Tissue Factor and CSC

Tissue Factor and Cancer Stem Cells. Is There a Linkage? by Chloe Milsom and 5 co-authors, including Janusz Rak, Arterioscler Thromb Vasc Biol 2009(Jul 23) [Epub ahead of print]. PubMed Abstract. Last sentence:

We propose that both tumor cell-associated and host-related TF could influence the properties of CSCs, and that agents targeting the TF/PAR system may represent a hitherto unappreciated therapeutic opportunity to control cancer progression by influencing the CSC/TIC compartment.