Search for prostate-cancer target identifies stem-cell population.[This article is not publicly accessible].
The cancer-stem-cell theory holds that tumours are formed by a very small population of self-renewing cells. The idea is controversial, but developmental biologist Wei-Qiang Gao hasn't allowed that to hamper his lab's quest to find such cells in the prostate. He and his colleagues have achieved an important first step — identifying the normal adult stem cells responsible for generating prostate tissue in mice.
Sunday, December 14, 2008
A first step toward identifying prostate CSC
Making the paper: Wei-Qiang Gao, Nature 2008(Dec 11); 456(7723): xiii [Published online 10 December 2008]. Excerpt: