OncoMed Pharmaceuticals, Inc. announced the publication in Cell Stem Cell of data demonstrating potent anti-cancer activity in colon and breast cancer models for the company’s first product candidate, OMP-21M18, underlining the therapeutic potential of targeting cancer stem cells to treat solid tumors. OMP-21M18 is currently in Phase 1 clinical testing.The publication: DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency by Timothy Hoey and 14 co-authors, including Michael F Clarke, John Lewicki and Austin Gurney, Cell Stem Cell 2009(Aug 7); 5(2): 168-77. [PubMed Citation][FriendFeed entry].[Full text of this "Featured Article", via Gratis OA][Full text PDF].
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