In a study published online in advance of print in Stem Cells, Tufts researchers report that the STAT3 gene regulates cancer stem cells in brain cancer. Cancer stem cells have many characteristics of stem cells and are thought to be the cells that drive tumor formation. The researchers report that STAT3 could become a target for cancer therapy, specifically in Glioblastoma multiforme (GBM), a type of malignant and aggressive brain tumor.See also: [Newswise][Insciences][EurekAlert][Medical News Today].
These News Releases are about this article: STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells by Maureen M Sherry and 4 co-authors, including Brent H Cochran, Stem Cells 2009(Aug 5) [Epub ahead of print]. [PubMed Citation].
Posts
See also: STATs in cancer inflammation and immunity: a leading role for STAT3 by Hua Yu, Drew Pardoll and Richard Jove, Nat Rev Cancer 2009(Nov); 9(11): 798-809 [PubMed Citation].
ReplyDelete